Film Independent Spirit Award-winner Patty Jenkins (Monster) along with Jennifer Aniston, Alicia Keys, and Demi Moore have been signed to direct the Lifetime Original Movie Project Five, an anthology of five short films exploring the impact of breast cancer on people’s lives. The film’s fifth director will be announced in the coming weeks.

Through its deeply interconnected story arc, Project Five will use humor and drama to focus on the effect that breast cancer and its diagnosis have on relationships and the way women perceive themselves, while searching for strength, comfort, medical breakthroughs and, ultimately, a cure.